Rootine Smart Multivitamin

Rootine delivers truly personalized vitamins based on your DNA, blood biomarkers, and lifestyle data. Each monthly subscription includes daily packs with 18 essential nutrients in microbeads, tiny slow-release particles calibrated to your body's exact needs. Unlike generic multivitamins, every dose is formulated specifically for you based on over 400 clinical studies.

About Rootine Smart Multivitamin

Rootine represents the cutting edge of personalized nutrition, moving beyond the one-size-fits-all approach of traditional multivitamins. Founded in 2018 by scientists frustrated with the guesswork of generic supplements, Rootine developed a system that uses your actual biological data, DNA, blood biomarkers, and lifestyle factors, to create a vitamin formula calibrated specifically for your body.

The science behind Rootine is substantial. Their personalization algorithm draws from over 400 peer-reviewed clinical studies examining how genetics affect nutrient absorption, metabolism, and requirements. When you provide DNA data (either through their test or uploaded from 23andMe/Ancestry), Rootine identifies genetic variants that influence how you process specific nutrients. Blood tests reveal your current vitamin and mineral levels, highlighting deficiencies and preventing over-supplementation. The lifestyle quiz captures factors like diet, exercise, sleep, and health goals that affect nutritional needs.

What arrives monthly isn’t a generic multivitamin, it’s 30 daily packs containing microbeads of 18 essential nutrients, each dosed precisely for you. The microbead format matters: these tiny slow-release particles improve absorption compared to traditional pills and allow for more accurate dosing than capsules that dump nutrients all at once.

Pricing Plans

Rootine uses a subscription model with optional testing add-ons:

Product	Price	Frequency	Notes
Smart Multivitamin	$94/month	Monthly (3-month auto-renew)	Core subscription
DNA Test	$115-125	One-time	Nutrigenetic analysis
Blood Vitamin Test	$127-149	Quarterly recommended	Current level check
Mineral Test	$127-149	Quarterly recommended	Mineral deficiency check
Cortisol Test	$118-139	As needed	Stress hormone analysis
Complete Bundle	$533	One-time	DNA + Blood + Mineral tests

Pricing Details:

• Smart Multivitamin subscription billed monthly, auto-renews every 3 months
• 3-month minimum subscription commitment
• Subscribe-and-save offers 15% off testing
• Can upload existing 23andMe or Ancestry DNA data free
• No refunds due to personalized manufacturing
• Cancel 30 days before next cycle to avoid charges

Annual Cost Estimate:

• Vitamins only: ~$1,128/year
• Vitamins + initial testing: ~$1,660 first year
• Vitamins + quarterly retesting: ~$2,100+/year

How It Works

1. Complete Lifestyle Assessment: Start with Rootine’s detailed quiz covering your diet, exercise habits, sleep patterns, health goals, and any existing conditions or medications. This takes about 10 minutes and provides baseline personalization.

2. Order DNA Test (Optional but Recommended): Rootine’s at-home DNA kit analyzes genetic variants affecting nutrient absorption and metabolism. Alternatively, upload existing data from 23andMe or Ancestry at no extra cost.

3. Complete Blood Tests (Optional but Recommended): At-home finger-prick tests measure your current vitamin and mineral levels, identifying deficiencies and preventing over-supplementation.

4. Wait for Analysis: DNA results take 3-5 weeks to process. Blood tests take about 1 week. Rootine’s algorithm combines all data with your lifestyle assessment to formulate your personalized vitamin blend.

5. Receive Your Personalized Formula: Your first shipment arrives containing 30 daily packs of microbeads with 18 nutrients dosed specifically for you. Each pack is labeled with your name and formula details.

6. Take Daily: Consume one pack daily, the microbeads can be swallowed with water, mixed into food, or added to smoothies. The slow-release format works throughout the day.

7. Retest and Optimize: Quarterly blood retesting (recommended) allows Rootine to adjust your formula as your levels change, ensuring ongoing optimization rather than static supplementation.

What’s Included

Each monthly Rootine shipment contains:

• 30 Daily Vitamin Packs: Individually sealed portions for each day
• 18 Essential Nutrients: Vitamins and minerals in personalized doses
• Microbead Delivery: Slow-release particles for optimal absorption
• Dosing Based on Your Data: Amounts calibrated to DNA, blood levels, and lifestyle
• Formula Documentation: Details on what’s in your specific blend and why

Who It’s For

Perfect For:

• Data-Driven Health Optimizers: Those who want supplementation based on actual biological data, not guesswork
• Biohackers and Self-Improvers: People tracking health metrics who want precision in their vitamin routine
• Those with Absorption Issues: Genetic variants affecting nutrient processing benefit most from personalization
• Athletes and Fitness Enthusiasts: Performance-focused individuals optimizing recovery and energy
• Busy Professionals: High-achievers willing to invest in premium health optimization

Consider Alternatives If:

• Budget is a Concern: At $94+/month plus testing, Rootine costs 5-10x more than standard multivitamins
• You Want Immediate Results: 3-5 week DNA processing means delayed start
• You Prefer Flexibility: 3-month commitment and no refunds limit options
• You’re Skeptical of Personalization Claims: Limited independent verification of algorithm efficacy
• You Just Want Basic Supplementation: Generic multivitamins may suffice for general wellness

The Science Behind Personalization

Rootine’s approach is based on nutrigenomics research:

Genetic Factors Considered:

• MTHFR variants affecting folate metabolism
• VDR variants affecting vitamin D absorption
• COMT variants affecting B vitamin needs
• APOE variants affecting omega-3 requirements

Blood Biomarkers Measured:

• Vitamin D levels
• B12 and folate status
• Iron and ferritin
• Zinc and magnesium

Lifestyle Factors Incorporated:

• Diet type and restrictions
• Exercise frequency and intensity
• Sleep patterns
• Stress levels and caffeine consumption

The algorithm combines these data points with over 400 peer-reviewed studies to generate personalized dosing recommendations.

Comparison with Alternatives

Service	Price	Personalization	Testing
Rootine	$94/mo + tests	DNA + Blood + Lifestyle	Comprehensive
Care/of	$30-50/mo	Quiz only	None
Persona	$40-80/mo	Quiz + health conditions	None
Baze	$70/mo	Blood test	Blood only
InsideTracker	Varies	Blood analysis	Blood only

Rootine offers the most comprehensive personalization but at the highest price point. The combination of DNA, blood, and lifestyle data is unique in the market.